Course: General and Inorganic Chemistry

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Course title General and Inorganic Chemistry
Course code 3150/F1AC1
Organizational form of instruction Lecture + Lesson
Level of course Master
Year of study not specified
Semester Winter
Number of ECTS credits 8
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Kos Jiří, PharmDr. Ph.D.
  • Kroutil Aleš, Mgr.
  • Goněc Tomáš, PharmDr. Ph.D.
  • Hudcová Anna, Mgr.
  • Marvanová Pavlína, PharmDr.
  • Padrtová Tereza, PharmDr.
Course content
Lectures Introduction and Importance of Chemical Sciences History Atom Quantum Theory Aufbau principle Chemical bond Hybridization MO Theory Delocalized bonds Ionic bond Hydrogen bond Metals Coordination compounds Chemical equilibrium Acids and bases Thermodynamics Chemical Kinetics Redox reactions Groups of Elements and their compounds important for pharmaceutical research and praxis. Intruduction to Bioinorganic Chemistry. A. Seminars 1. Basic concepts. Chemical nomenclature. Oxidation number. All chemical symbols. Periodic Table. Naming of elements, oxides, acids, acid derivatives, hydroxides, salts. Binary compounds (hydrides, peroxides, sulfides, nitrides, carbides). 2. Revision of nomenclature. Electron structural formulas. Octet rule. The formal charge. 3. Continuous test (terminology, formulas and equations, about 15 minutes, 10 points). Amount of substance (the conversion of grams per mole). The calculation of chemical formula from elemental analysis. Chemical equation. Balancing equations. Redox equations. Revision of nomenclature. 4. Solutions. Calculation of molar concentration. Calculations of pH. VSEPR theory. 5. Stoichiometry - material balance. Theoretical reaction proceeds. Solubility, crystallization proceeds. Nomenclature of coordination compounds. 6. Final exam B. Experimental work in laboratory 7. Synthesis of boric acid (ortho-boric acid). 8. Synthesis of disodium [tetrahydroxo-pentaoxotetraborate] octahydrate. 9. Synthesis of lead(II) iodide. 10. Preparation of metallic copper and ferrous sulphate pentahydrate. 11. Preparation of iron(III) oxide (precipitation and annealing) or ferrofluid (magnetic nanoparticles). 12. Molecular graphics of inorganic and coordination molecules. Computer room.

Learning activities and teaching methods
unspecified
Learning outcomes
The students will be acquainted with the subject of chemistry including the basic branches of chemistry and the importance of chemistry for pharmacists. The course will focus on the following items: fundamental chemical terms and laws, equations for calculating the quantity of substance and concentration, atomic structure, radioactivity, basic equations used in spectral analysis, models of atomic orbitals, chemical bond including hybridization, physical states of matter, the periodic law and the classification of elements including forms and the division of the periodic system into groups, and the properties of individual elements in the periodic table. Seminars will concentrate on problems such as calculating the amount of substance, composition of solutions, diluting and mixing solutions, formation of chemical formulas and balancing equations for stoichiometric calculations, and the calculation of the pH. During practical exercises, the students will be acquainted with the basics of laboratory work and will also prepare some inorganic compounds according to calculated equations. The students will elaborate protocols containing the description of the principle of the method and all calculations including the calculation of theoretical yield which will be compared with the practical yield obtained.

Prerequisites
unspecified

Assessment methods and criteria
unspecified
Recommended literature
  • Flemr, V., Holečková, E. Úlohy z názvosloví a chemických výpočtů v anorganické chemii. Praha, VŠCHT, 2001. ISBN 978-80-7080-435-3.
  • Galamboš M. a kol. Názvoslovie anorganických látok.Princípy a príklady.. Bratislava, UKO, 2009. ISBN 978-80-223-2.
  • Greenwood N.N., Earnshaw A. Chemistry of the Elements. Amsterdam, Elsevier, 2010. ISBN 9780750633659.
  • Klikorka, Jiří - Hájek, Bohumil - Votinský, Jiří. Obecná a anorganická chemie. Praha, 1989.
  • Krätsmár-Šmogrovič, J. a kol. Všeobecná a anorganická chémia. Ostrava, 2007.
  • Polák, R., Zahradník, R. Obecná chemie: stručný úvod. Praha, Academia, 2000. ISBN 80-200-0794-6.
  • Ulická, Ľ., Ulický, L. Príklady zo všeobecnej a anorganickej chémie. 2. vyd.. Bratislava, 1987.


Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester
Faculty of Pharmacy Pharmacy (1) Pharmaceutical sciences 1 Winter