Course: Medical Forms and Biopharmacy I

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Course title Medical Forms and Biopharmacy I
Course code 3130/F1FO1
Organizational form of instruction Lecture + Lesson
Level of course Master
Year of study not specified
Semester Winter
Number of ECTS credits 5
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Masteiková Ruta, Doc. PharmDr. CSc.
  • Kubová Kateřina, Doc. PharmDr. Ph.D.
  • Gajdziok Jan, Doc. PharmDr. Ph.D.
  • Franc Aleš, PharmDr. Ph.D.
  • Vysloužil Jakub, PharmDr. Ph.D.
  • Lukášová Ivana, PharmDr.
  • Sabadková Dana, Mgr.
  • Pavelková Miroslava, PharmDr.
  • Pechová Veronika, PharmDr.
  • Vodáčková Pavlína, PharmDr.
  • Naiserová Martina, Mgr.
  • Tkadlečková Veronika, Mgr.
Course content
SYLLABUS OF LECTURES 1. Introduction into Medical Forms and Biopharmacy. Solutions: basic methods of preparation, quality evaluation. 2. Excipients for preparation of liquid dosage forms (solutions). Water for pharmaceutical purposes. 3. Sterilization techniques. Requirements for the preparation of sterile medications. 4. Ophthalmic preparations - definition, classification, preparation, quality evaluation; bioavailability of drugs from ophthalmic products. 5. Preparations intended for nasal and ear application. 6. Pharmaceutical emulsions - definition, classification, preparation, quality evaluation. Physical aspects of emulsions. 7. Pharmaceutical suspensions - definition, classification, preparation, quality evaluation. 8. Incompatibilities in pharmaceutical dosage forms. 9. Excipients for preparation of suspensions and emulsions. 10. Powders, classification, particle size and the influence of particle size on the bioavailability of drugs; preparation, application and quality evaluation. 11. Parenteral dosage forms. 12. Topical semusolid preparations: definition, classification, properties, excipients. 13. Topical semisolid preparations: preparation and quality evaluation. PRACTICAL TRAINING 1. Introduction to the practical training. Pharmaceutical calculations. 2. Medicinal solutions: preparation at room and higher temperature, evaluation. 3. Medicinal solutions: preparation by solubilization and chemical reaction, evaluation. 4. Aromatic waters and spirits. Syrups. Infusions and decoctions. Mucilagines. Preparation and evaluation. 5. Eye drops. Preparation and evaluation. 6. Nasal and ear drops. Preparation and evaluation. 7. Emulsions. Preparation and evaluation. 8. Suspensions. Preparation and evaluation. 9. Preparation of liquid dosage forms according to prescriptions. 10. Divided and non-divided pharmaceutical powders. Preparation and evaluation. 11. Alternative training. 12. Test and check training. 13. Awarding credits.

Learning activities and teaching methods
unspecified, unspecified, unspecified, unspecified, unspecified
Learning outcomes
One of the main obligatory pharmaceutical disciplines dealing with preparation, manufacturing and quality control of medicaments including technological procedures, equiment, excipients and appropriate analytical devices. It covers the influence of the application form on drug bioavailability.

Prerequisites
unspecified

Assessment methods and criteria
unspecified
Recommended literature
  • Časopis Česká a slovenská farmacie.
  • Český lékopis - platné vydání a doplňky.
  • Chalabala, M., Heinrich, J. Základy výroby a tvorby liekov. Osveta Martin, 1988.
  • Komárek, P., Rabišková, M. Technologie léků. Galén, Praha, 2006. ISBN 80-7262-423-7.
  • Zathurecký, L., Chalabala, M., Janků, I., Modr., Z. Biofarmácia a farmakokinetika. Osveta Martin, 1989. ISBN 80-217-0068-8.


Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester
Faculty of Pharmacy Pharmacy (1) Pharmaceutical sciences 4 Winter