Course: Pharmacognosy II

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Course title Pharmacognosy II
Course code 3120/FAFG2
Organizational form of instruction Lecture + Lesson
Level of course Master
Year of study not specified
Semester Summer
Number of ECTS credits 10
Language of instruction English
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Khazneh Elian, Bc.
  • Šmejkal Karel, Doc. PharmDr. Ph.D.
  • Kaucká Petra, PharmDr. Ph.D.
  • Treml Jakub, PharmDr. Ph.D.
  • Sychrová Alice, PharmDr. Ph.D.
  • Valentová Marie, PharmDr. Ph.D.
  • Neuwirth Ondřej, Mgr.
  • Hanáková Zuzana, PharmDr. Ph.D.
Course content
Syllabus of lectures " Drugs affecting the central and periferal nervous system " Drugs affecting vegetativ nervous system " Drugs affecting cardiovascular system " Drugs affecting hemokoagullation, fibrinolysis an use as nahrada blood plasma " Drugs affecting water balance of the organism " Drugs affecting respiratory system " Drugs affecting digestive system " Uterotonics, antiuratics, antiflogistics " Dietetics, roborans, geriatrics; sources of vitamins; pomocní léčba od diabetes mellitus " Hormones, enzymes " Antiinfectious and intiinvasiv drugs " Drugs using for their local activity " Pomocné farm. látky biogenního původu " Natural substances inspirational for synthesis Laboratory practice ? summer half 1. Drugs containing saccharides Identification Tests of purity 2. Drugs containing polysaccharides and mucilages Identification Determination of swelling number 3. Drugs containing phenolic glycosides Identification Chromatographic proof of arbutine and hydroquinone Titrating determination of arbutine 4. Drugs containing cardioglycosides (Control test I) Identification Chromatographic proof Colorimetric determination 5. Drugs containing antraquinone glycosides Identification Chromatographic proof Colorimetric determination of hypericine 6. Drugs containing flavonoid glycosides Identification Colorimetric determination of flavonoids Chromatographic proof 7. Drugs containing saponins (Control test II) Identification Determination of hemolytic activity on blood agar Determination of number of foamability according Kofler Determination of glycyrrhizinic acid 8. Drugs containing tannins Identification ? color and precipitation reactions Chromatographic proof Colorimetric determination 9. Drugs containing volatiles Identification Chromatographic proof Hydro distillation determination 10. Drugs containing alkaloids I. (Control test III) Identification ? color and precipitation reactions Titration determination of tropane alkaloids 11. Drugs containing alkaloids II. Identification ? color and precipitation reactions Gravimetric determination of purine alkaloids Thin layer chromatography of poppy opium alkaloids 12. Drugs containing bitter substances Identification Determination of number of bitterness 13. Drugs containing mustard glycosides Identification and purity 14. Drugs containing coumarins, anthocyanins (Control test IV) Chromatographic proof

Learning activities and teaching methods
unspecified, unspecified, unspecified, unspecified, unspecified
Learning outcomes
Objectives of Pharmacognosy are to impart knowledges of those drugs of biological origin and their constituents that are of value for their therapeutic, profylactic and diagnostic use in the human and veterinary medicine. Its scope includes the study of the physical, chemical, biochemical and biological properties of drugs, drug substances, or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources. Research problems in pharmacognosy include studies in the areas of phytochemistry, microbial chemistry, biosynthesis, biotransformation, chemotaxonomy, and other biological and chemical sciences. Pharmacognosy represents a highly interdisciplinary science which is one of five major areas of pharmaceutical education.

Prerequisites
Knowledge of organic chemistry, analytical chemistry, phytochemistry, biochemistry, physiology. This knowledge will be strictly demanded.

Assessment methods and criteria
unspecified
Required for crediting: 100% attendance of all the practices Passing the written tests (60% is required to pass) Required for examination: Basic knowledge of plant secondary metabolism, structures of pharmaceutically, pharmacologically, or toxicologically important compounds, drugs and plant names, pharmacological or technological effectsand usage, basic methods for identification and quanification. Apart of pharmacognosy examination is macroscopic recognition of 10 drugs and microscopic identification of three preparates.
Recommended literature
  • Bruneton Jean. Pharmacognosy, Phytochemistry, Medicinal Plants . 1999. ISBN 1898298637.
  • Evans W Ch. Trease and Evans' Pharmacognosy. 2009. ISBN 9780702029332.


Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester
Faculty of Pharmacy - (12) Pharmaceutical sciences 3 Summer